Nationwide antibody study
on the spread of SARS-CoV-2 infection

Multi-local and serial cross-sectional prevalence study on antibodies against SARS-CoV-2 in Germany

The actual Seroprevalence Seroprevalence denotes the proportion of people in a population who test seropositive for a specific infectious agent, as measured by blood tests (serological tests). It is often reported as a weighted percentage of the total number of samples tested. caused by COVID-19 in the population is crucial to a possible Underreporting Under-coverage (statistical unit) denotes incomplete coverage in which only a more or less large part of a total is reached. Under-reporting of COVID case numbers is due to a failure to report by doctors or due to a non-doctor's visit (slight disease progression). to better understand infected people and to make decisions about possible continuation or termination of Interventions Interventions are planned and targeted measures to prevent or remedy the spread of cases and to contain negative consequences. and also the precise determination of Mortality rates Mortality rates also called mortality (mortality rate), is defined as the number of deaths during a certain period in relation to the population at risk. and to enable severe disease processes.



The Study

Determine immunity

The aim of this study is to determine the actual spread of SARS-CoV-2 infections and the corresponding immunity in different population groups in Germany.


Worldwide quarantine

Since the novel coronavirus SARS-CoV-2 emerged in December 2019, many countries around the world have quarantined their populations, including Germany.

Data protection & Ethics


The data protection concept describes the data protection and IT security measures for the “MuSPAD” study of the Helmholtz Centre for Infection Research and meets the requirements of the General Data Protection Regulation (GDPR).



We are working closely with partly known partners, some counties as well as public health departments to ensure a smooth running of the study.

Register here

Get involved: Research can only happen if people like you get involved. Be part in our MuSPAD research! Everybody makes a difference.

Hotline number for booking an appointment: 030 / 78783-3107

Please have your appointment code ready, which you received with the invitation letter! By the way, your invitation letter also acts as entry ticket.

From 07.04.2021 to 05.05.2021 we are on the road in Madgeburg.



Reasons to participate

Why should i take part?

Make time for our research

A participation in the study will help to better understand the incidence of SARS-CoV-2 in Germany.

Invitation process

Take part

Participants in the study are randomly selected per region from local registration offices.


Study sites


Eight counties across Germany will be selected as study site.

Study design

Study procedure

Before the actual blood sampling, an appointment must be made by phone or web-based.

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